In January 1993, Datuk Mohd Nasir was seconded to TNB’s subsidiary company, Malaysia Transformer Manufacturing Sdn Bhd, as Financial Controller before being appointed its Chief Executive Officer (CEO) in June 1994.
In January 2000, he joined Sharikat Permodalan Kebangsaan Berhad as its CEO. On 1 June 2001, he was appointed CEO of Perbadanan Usahawan Nasional Berhad, a position he held until his retirement on 1 June 2011.
Datuk Mohd Nasir also holds directorships in private companies, namely CIMB EOP Management Sdn Bhd and Touch n’ Go Sdn. Bhd.
In addition, he is also a Trustee of Yayasan Canselor UNITEN, Perdana Leadership Foundation and Chairperson of CIMB Foundation.